产品编号：KMPH1835

产品名称：Recombinant Human ACE2 Protein, His-tag

产品别称：Angiotensin-converting enzyme 2, ACE2

规格：100ug，1mg

物种：Human

宿主：HEK293 Cells

序列：18-740AA

来源：A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was

expressed with a polyhistidine tag at the C-terminus.

纯度：≥95% as determined by SDS-PAGE

内毒素水平：< 1.0 EU per μg of the protein as determined by the LAL method.

缓冲体系：Lyophilized from sterile PBS, pH 7.4.

纯化方式：His Tag Purification

产品背景：

Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell

membranesofcellslocatedinthelungs,arteries,heart,kidney,andintestines.

ACE2lowersbloodpressureby catalyzing thehydrolysisof angiotensinIIinto

angiotensin (1–7). ACE2 counters the activity of therelated

angiotensin-convertingenzyme(ACE)by reducingtheamountofangiotensin-II and

increasing Ang(1-7), making it a promising drug target for treating cardiovascular 

diseases.ACE2alsoserves asthe entrypointintocellsforsome coronaviruses, including

HCoV-NL63, SARS-CoV, and SARS-CoV-2.

保存条件：Store the product under sterile conditions after opening at -20℃ to -80℃ for 12

months. Avoid repeated freeze-thaw cycles.

运输条件：Liquid product is shipped on dry ice; Lyophilized powder is shipped on ice packs